DON WHITLEY SCIENTIFIC – THE LEADING INTERNATIONAL SUPPLIER TO THE MICROBIOLOGY AND TISSUE CULTURE INDUSTRIES


Contact Us +44 (0) 1274 595728 sales@dwscientific.co.uk

Follow Don Whitley Scientific

Useful Links

Clostridium difficile studies can be done in a Whitley Workstation

An exciting opportunity to join our sales team

Anyone interested in an exciting opportunity to move into sales?

Don Whitley Scientific now has a vacancy for a Technical Sales Representative.

The Role

As a Technical Sales Representative you will promote an exciting range of laboratory equipment and service contracts. Brands include Whitley Anaerobic, Hypoxic and Microaerobic Workstations, Whitley Automated Spiral Plater plus products such as the automated specimen processor WASPLab, media/sample preparation equipment and other niche laboratory equipment.

This role will provide an opportunity for the successful candidate to further develop an established customer base and build a long-term, lucrative career in the UK as well as the possibility of overseas travel.

Candidates with no previous sales experience will be considered as training will be provided. A high level of support will also be available from senior colleagues.

 

Core responsibilities include:

  • Maximising sales potential and business growth by establishing relationships and collaborations with customers.
  • Working closely with marketing to ensure relevant promotions are delivered to customers and that feedback from customers is relayed back to inform future planning.

Essential Requirements:

  • Highly motivated and ambitious.
  • Hands-on approach and comfortable with daily travel.
  • Articulate, confident communicator able to engage with people at all levels, including technical managers and procurement/finance personnel.
  • Independent and decisive, using creative thought and sound logic to identify, prioritise and maximise opportunities.
  • Based in the north of England to serve a territory that extends into Scotland.

Our sales team comprises of successful people with and without a science background, so experience in a scientific discipline is not a prerequisite.

 

Remuneration

Package includes:

  • Basic salary dependent upon experience
  • Attractive bonus scheme
  • Company car

How to apply

Please email Steve Robertson, Sales Director on steve_robertson@dwscientific.co.uk attaching a current CV.

STRICTLY NO AGENCIES

removal van

Don Whitley Scientific to Move to Bingley

After 40 years of manufacturing in Shipley, Don Whitley Scientific Limited has announced that the company will move to new premises in Bingley.

 

 

 

 

Managing director, Paul Walton, explains:Paul Walton
“Our business has expanded considerably, particularly over the last 10 years, and despite having purchased numbers 16 and 18 Otley Road, we have still outgrown our current facilities. When Victoria Works came up for sale, providing 48,100 sq ft, we knew this would be the right move for us. The Bingley premises will provide us with the space to organise ourselves more efficiently and still have room to expand.”

 

 

 

The new premises, just off Bradford Road, is undergoing a major refit (by Eclipse Interiors) to make it suitable for the company’s needs. There will be considerably more warehousing capacity plus new offices, a bespoke production area, service centre, R&D mezzanine and improved staff facilities including a large, fully fitted, air-conditioned canteen. There will also be a new product showroom where customers can view demonstrations of the latest anaerobic and hypoxic workstation technology.

 

 

The office for sales, service and marketing

The office for sales, service and marketing

Warehouse area

Warehouse area

 

 

 

 

 

 

 

 

 

 

Product showroom

Product showroom

 

 

 

 

 

 

 

 

 

 

 

 

The move will take place from 13 to 17 June so the business will be operational from Bingley on Monday, 18 June.

 

Whitley Hypoxystation

World Heart Day: Hypoxia in Cardiovascular Disease Research

Cardiovascular disease, including heart disease and stroke, is responsible for approximately 1 in 3 deaths in the US, according to the American Heart Association. World Heart Day on 29 September serves as a platform to educate people on how to take control of their heart health.

Don Whitley Scientific and our US/Canadian distributor HypOxygen would like to take this opportunity to highlight cardiovascular research being carried out around the world – and to say “thank you for being committed to our health.”

Adverse cardiac remodeling after infarction exacerbates myocardial ischemia and increases the likelihood of heart failure. Revuelta-Lopez et al. in Spain present new data showing that in the hypoxic areas of the infarct zone, expression of low-density lipoprotein receptor-related protein 1 (LRP1) is linked to activation of Matrix metalloproteinase (MMP) through Pyk2 phosphorylation, and propose that LRP1 modulation may be a very effective pharmacological target in heart disease. Their H35 Hypoxystation with its controlled low oxygen environment creates physiologically more relevant parameters for cell culture, mimicking ischemia/reperfusion events.

Hypothesizing that Tumor necrosis factor-Related Apoptosis-Inducing Ligand plays a role in ischemic injury during acute myocardial infarction, Jiang et al. have found evidence for a novel immune regulatory mechanism involving TRAIL, ER stress and NF-κB signaling pathways. Culturing their cells in the Hypoxystation H35 at 0.3% oxygen allowed the lab to simulate the ischemia/reperfusion processes that cause cardiomyocyte loss and increase mortality in Coronary Heart Disease.

Hypoxia in the embryonic environment supports maintenance of a primitive glycosaminoglycan-rich heart valve matrix, the specific composition of which determines proper function, and as hypoxia decreases after birth, the extracellular matrix matures. Amofa et al. at Cincinnati’s Children’s Medical Center, using the H35 Hypoxystation, provide new data that exposure of adult heart tissue to hypoxia induces hyaluronan remodeling, GAG accumulation, and degeneration of the extracellular matrix in the heart valve, effects that are implicated in Myxomatous mitral valve disease.

Dr. Michael Cross, Molecular and Clinical Pharmacology Department, University of Liverpool, says of his work with cardiac spheroids : “The H35 allows us to generate oxygen levels that reflect the in vivo physiology these cells would be exposed to. We chose the Hypoxystation with its oxygen profiling feature, which allows us to recreate cycles of ischemia, where oxygen levels typically sink to 1-3%”.

Revuelta-Lopez et al 2017

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Image from: Revuelta-Lopez et al. “Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction” J Cell Mol Med. 2017 Sep;21(9):1915-1928

 

Amofa et al 2017

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Hypoxia increases GAGs, Sox9 nuclear localization and Hyal2 expression in cAVOCs.

Image from: Amofa et al. (2017) “Hypoxia promotes primitive glycosaminoglycan-rich extracellular matrix composition in developing heart valves” Am J Physiol Heart Circ Physiol. 2017 Aug 25:ajpheart.00209.2017

 

 

 

Dr John Heap, Imperial College London

Realising the potential for synthetic biology

At Don Whitley Scientific we love to hear about the different applications and scientific disciplines in which our workstations are used. We recently came across a video of a presentation at the World Economic Forum in 2015. The clip is entitled: “Hacking exotic organisms and putting them to work“. Dr John Heap, who is an academic scientist and research group leader at Imperial College London, talks about harnessing diverse organisms including anaerobic bacteria, and realising the potential of synthetic biology for a variety of applications.

You will also see a very quick shot of Dr Heap using his Whitley Workstation!

For more information about Dr Heap and his work, here’s a link to the Heap Lab website.

 

Biomedical Scientist_Clinical Microbiology of Anaerobes Course

Interactive Flip-book Brochures From Don Whitley Scientific

Interactive brochures from Don Whitley Scientific offer a novel way to find out about anaerobic, microaerobic and hypoxic workstations. 

The Anaerobic and Microaerobic Workstations guide features information on Whitley Workstations that are suited to clinical environments, contract laboratories and research institutions. The guide also provides information on the features that make these systems unique, offering in-depth detail on the options available to tailor-make a workstation to a user’s requirements.

The Hypoxia and Cell Culture Workstations brochure provides information on how Whitley Hypoxystations provide the fastest oxygen control on the market. This document introduces the range of workstations that allow researchers to grow and manipulate cells in                                                                                physiologically relevant conditions.

hypoxic-brochure

anaerobic-and-microaerobic-workstations

 

 

Benchtop Autoclaves Comp50

Did You Know: You need to use the appropriate autoclave cycle for different load types?

Unlike their medical counterparts, laboratory autoclaves need to be capable of running a variety of different sterilisation cycles, for liquids, instruments and waste. 

Each of these cycles has unique requirements and the unit should be equipped to meet these varying needs. Cycles should be specific to the load type with parameters designed to meet proper sterilisation. An example of these required cycles would be when it comes to autoclaving hollow items such as tubing sets, which are frequently used but often inadequately sterilised. For such items, cycles need to be used that use a prefractionated vacuum that eliminates air pockets and maximises steam penetration.

During liquid sterilisation, most autoclaves reach a certain temperature measured inside of the vessel that corresponds to the steam inside the chamber, for a certain length of time, without ever measuring the specific temperature of the liquids to be sterilised.  Many laboratories would be surprised to find that their liquids never reach sterilisation temperature at any point during the sterilisation time even though the autoclave chamber temperature has reached 121 degrees Celsius.

To ensure liquids reach sterilisation temperature, Tuttnauer autoclaves employ the use of a flexible PT 100 temperature probe. The PT 100 extends down into the sterilisation chamber and measures the temperature in a reference vessel; the autoclave’s temperature and run time are based on this liquid temperature, not the temperature of the sterilisation chamber.

Don Whitley Scientific is accredited by UKAS to provide calibration and validation services for heat sterilisation equipment, temperature controlled processes and temperature indicators. This service is vital to make sure autoclaves are running efficiently and appropriately, and this level of after sales support sets Don Whitley Scientific apart from other autoclave suppliers.

Learn more about Tuttnauer Laboratory autoclaves

This is another article in the ‘Did you know’ series, introducing facts you may not know about products and services supplied by Don Whitley Scientific.


New Cancer Mutation Tracking Blood Test

Researchers at the Institute of Cancer Research, London found traces of breast cancer eight months before doctors would normally have noticed. A new study suggests that a blood test may be able to save lives by finding cancers that have started to grow again after treatment. See the full story at http://www.icr.ac.uk/news-archive/new-mutation-tracking-blood-test-could-predict-breast-cancer-relapse-months-in-advance 

 

Laboratory Standard Shot DYK Blog

Did you know: How best to clean your workstation?

 

 

This is the 10th in our ‘Did you know’ series of articles introducing things you may not know about the Whitley range of products and services – read on and you may find out something about your workstation that could make your working life easier.

We regularly receive enquiries from customers with regard to which disinfectants can be safely used inside Whitley Workstations. Although it is not practicable to evaluate every available product, we have tested the materials compatibility of several sporicidal disinfectants and can now provide comprehensive advice on this topic.

 

 

How often should I clean my workstation?

DWS recommend that as part of the daily checks, users ensure that the workstation is free from spillage and cleaning carried out as necessary. Prior to having your workstation serviced, however, it may be necessary for it to be decontaminated.

Which disinfectants have DWS tested?

  • Spor-Klenz – peracetic acid (approx 0.1%) + hydrogen peroxide (approx 1.0%) – “ready to use” product, tested without further dilution.
  • Chemgene HLD4H – quaternary ammonium compounds (approx 1%) + chlorhexidine digluconate (approx 1%) – “ready to use” product, tested without further dilution.
  • Safe Hospital – hypochlorous acid – “ready to use” product, tested without further dilution.
  • Tristel Fuse – chlorine dioxide (approx 1%) – prepared from concentrated components according to manufacturer’s instructions.

For more information on these tests, please see the appendices of your Whitley Workstation user manual.

 

Which of the above products are OK for use in a Whitley Workstation?

Our tests demonstrated that each of these formulations is satisfactory for use in Whitley Workstations and will not cause any damage when used in accordance with the manufacturer’s recommendations.

 

What if I want to use a cleaning agent not on the above list?

Other disinfectants containing the active ingredients listed above, at similar concentrations to those shown, can also be safely used inside Whitley Workstations. If you wish to use a disinfectant containing active ingredients not listed here, please contact us for advice before proceeding.

 

Why should I contact DWS for advice – will any damage not be covered under my warranty?

Unfortunately, we cannot cover under the equipment’s warranty any damage caused to a Whitley Workstation as a result of exposure to products that have not been approved by us.

 

Can I use Virkon as my preferred sanitising solution?

After a thorough study lasting 20 weeks, we concluded that the presence of any uncovered containers of Virkon in anaerobic and variable atmosphere workstations leads to the degradation of stainless steel, brass and some other metal components. The effect is more considerable when oxygen is present in the selected gas mixture. These conclusions are supported by technical information available on the Virkon manufacturer’s website and independent observations by an Institute of Materials metallurgist. If Virkon is the preferred sanitising solution these adverse effects can be minimised by ensuring that Virkon within any workstation is always kept in a covered vessel when not in use.

 

OK, so what’s the best way to clean the acrylic parts of a Whitley Workstation?Labdet100 Blog

The transparent and/or white acrylic on the inside and outside of the Whitley Workstation System may be swabbed with a 2% solution of Labdet 100 (DWS – stock code D00003) in warm water and dried afterwards with a soft clean cloth. In the case of culture spillages then any of the disinfectants listed above solution should be applied to the spillage and left for 30 minutes. It should then be mopped.

 

Never use any solvent on the acrylic surfaces of the workstation. Use only water and a mild detergent solution (i.e. Labdet 100 2% solution) as a cleaning agent.

 

What if the spillage leaks underneath the floor of the workstation?

If spillage is not contained on the working surface then access underneath this area will be required in all Whitley Workstations except the DG250. Some workstations require the removal of retaining bolts before the floor can be lifted up or pivoted for cleaning underneath.

If liquid has been spilled upon the Anotox and catalyst sachets they should be removed, dried and/or replaced.

 

How can I deal with scratches on the acrylic plastic surface of my workstation?

Scratches may be removed by gently polishing the surface with ‘DURAGLIT WADDING’ followed by wiping with a soft clean cloth. Deep scratches may require the use of Wet and Dry abrasive paper used wet, followed by polishing with ‘DURAGLIT’ – seek advice from Don Whitley Scientific Limited or our authorised agents overseas.

 

How can I clean the sleeves on my workstation?Sleeve Kit-Components DYK Blog

The white sleeves used on all Whitley Workstations may require cleaning after periods of extended use. There are a number of options for cleaning and some recommendations listed below:

  • Wipe with a mild detergent
  • Wash or dry-clean with a detergent up to 75ºC
  • For disinfection use Sodium Hypochlorite (at no more than 1000ppm active Chlorine) or any of the disinfectants listed above
  • Do not use Biological or Phenolic based cleaners
  • Wash and dry completely before storage
  • Some surface wrinkling may occur.

 

If you have any remaining concerns about disinfectants for use in Whitley Workstations, please get in touch with our sales team:

Tel: 01274 595728

Or

Email: sales@dwscientific.co.uk

 

A leading Canadian scientist uses the Whitley Hypoxystation to make breakthrough discoveries in how cells function in low oxygen environments.

Dr Stephen Lee, a professor in the Department of Cellular and Molecular Medicine at the University of Ottawa, has published a paper that answers the question: “how do bodily cells function when at high altitude where the air contains little oxygen?”

Read more